PHILADELPHIA -- Researchers long thought that only one strand of a double-stranded microRNA can silence genes. Though recent evidence has challenged that dogma, it's unclear what the other strand does ...
Among the large, diverse set of mammalian long noncoding RNAs (lncRNAs), long noncoding primary microRNAs (lnc-pri-miRNAs) are those that host miRNAs. Whether lnc-pri-miRNA loci have important ...
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Multi-fluid microRNA signals as markers of endometriosis
By Dr. Liji Thomas, MD By analyzing microRNAs in blood, saliva, and vaginal mucus, researchers uncover fluid-specific molecular patterns that could inform future noninvasive diagnostics for ...
MicroRNAs, whose discovery was recognized with the 2025 Nobel Prize in Physiology or Medicine, are central regulators of gene ...
Our brains contain billions of neurons and trillions of connections, and scientists are only beginning to understand the intricate process required to build this level of complexity. This includes ...
microRNAs (miRNAs) are essential regulators of gene expression in diverse biological processes and disease states. They are short 22-nt noncoding RNAs that bind to mRNA targets via partial base ...
Potential of Field Is Catalyst for Emerging Diagnostic and Therapeutic Strategies As key regulators of gene expression and cellular machinery, microRNAs may be the most significant discovery in ...
Study links exosomal microRNA to ventricular remodelling in heart failure. Discover how this biomarker could inform future ...
microRNAs (miRNA), non-coding RNA molecules, are widely known for regulating mRNA stability and translation. miR-10b has been increasingly implicated in the pathogenesis of gliomas, cancers of the ...
The 2024 Nobel Prize in Physiology or Medicine was awarded to Victor Ambros and Gary Ruvkun for their groundbreaking discovery of microRNA and its pivotal role in post-transcriptional gene regulation.
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